USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: 1433T_HUMAN USC-OGP 2-DE database:  1433T_HUMAN 1433T_HUMAN General information about the entry View entry in simple text format Entry name 1433T_HUMAN Primary accession number P27348 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=14-3-3 protein theta; AltName: Full=14-3-3 protein T-cell; AltName: Full=14-3-3 protein tau; AltName: Full=Protein HS1;. Gene name Name=YWHAQ Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0167: pI=4.65; Mw=28492 Cross-references UniProtKB/Swiss-Prot P27348; 1433T_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name 1433T_HUMAN Primary accession number P27348 Secondary accession number(s) D6W4Z5 Q567U5 Q5TZU8 Q9UP48 Sequence was last modified on  August 1, 1992 (version 1) Annotations were last modified on  March 15, 2017 (version 188) Name and origin of the protein Description RecName: Full=14-3-3 protein theta; AltName: Full=14-3-3 protein T-cell; AltName: Full=14-3-3 protein tau; AltName: Full=Protein HS1; Gene name Name=YWHAQ Encoded on Name=YWHAQ Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X56468; CAA39840.1; -; mRNA EMBL X57347; CAA40622.1; -; mRNA EMBL BT020014; AAV38817.1; -; mRNA EMBL CH471053; EAX00977.1; -; Genomic_DNA EMBL CH471053; EAX00979.1; -; Genomic_DNA EMBL BC050601; AAH50601.1; -; mRNA EMBL BC056867; AAH56867.1; -; mRNA EMBL BC093019; AAH93019.1; -; mRNA EMBL AF070556; AAC28640.1; -; mRNA CCDS CCDS1666.1; -; . PIR S15076; S15076; . RefSeq NP_006817.1; NM_006826.3; . UniGene Hs.74405; -; . PDB 2BTP; X-ray; 2.80 A; A/B=1-234 PDB 5IQP; X-ray; 2.60 A; A/B=1-245 PDBsum 2BTP; -; . PDBsum 5IQP; -; . ProteinModelPortal P27348; -; . SMR P27348; -; . BioGrid 116168; 430; . DIP DIP-27584N; -; . IntAct P27348; 107; . MINT MINT-121282; -; . STRING 9606.ENSP00000238081; -; . iPTMnet P27348; -; . PhosphoSitePlus P27348; -; . SwissPalm P27348; -; . DMDM 112690; -; . OGP P27348; -; . REPRODUCTION-2DPAGE IPI00018146; -; . EPD P27348; -; . MaxQB P27348; -; . PaxDb P27348; -; . PeptideAtlas P27348; -; . PRIDE P27348; -; . TopDownProteomics P27348; -; . DNASU 10971; -; . Ensembl ENST00000238081; ENSP00000238081; ENSG00000134308; . Ensembl ENST00000381844; ENSP00000371267; ENSG00000134308; . GeneID 10971; -; . KEGG hsa:10971; -; . UCSC uc002qzx.5; human; . CTD 10971; -; . DisGeNET 10971; -; . GeneCards YWHAQ; -; . H-InvDB HIX0077146; -; . HGNC HGNC:12854; YWHAQ; . HPA CAB010286; -; . HPA HPA007925; -; . MIM 609009; gene; . neXtProt NX_P27348; -; . OpenTargets ENSG00000134308; -; . PharmGKB PA37443; -; . eggNOG KOG0841; Eukaryota; . eggNOG COG5040; LUCA; . GeneTree ENSGT00760000119116; -; . HOGENOM HOG000240379; -; . HOVERGEN HBG050423; -; . InParanoid P27348; -; . KO K16197; -; . OMA SGDDRKQ; -; . OrthoDB EOG091G0VKY; -; . PhylomeDB P27348; -; . TreeFam TF102002; -; . Reactome R-HSA-111447; Activation of BAD and translocation to mitochondria; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-5625740; RHO GTPases activate PKNs; . Reactome R-HSA-5628897; TP53 Regulates Metabolic Genes; . Reactome R-HSA-75035; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; . SignaLink P27348; -; . SIGNOR P27348; -; . ChiTaRS YWHAQ; human; . EvolutionaryTrace P27348; -; . GeneWiki YWHAQ; -; . GenomeRNAi 10971; -; . PMAP-CutDB P27348; -; . PRO PR:P27348; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000134308; -; . CleanEx HS_YWHAQ; -; . ExpressionAtlas P27348; baseline and differential; . Genevisible P27348; HS; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:GOC; . GO GO:0043234; C:protein complex; IDA:MGI; . GO GO:0047485; F:protein N-terminus binding; IPI:UniProtKB; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0034766; P:negative regulation of ion transmembrane transport; IEA:Ensembl; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; IDA:BHF-UCL GO GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome; . GO GO:0006605; P:protein targeting; IEA:Ensembl; . GO GO:0007264; P:small GTPase mediated signal transduction; IEA:Ensembl; . GO GO:0021762; P:substantia nigra development; IEP:UniProtKB; . Gene3D 1.20.190.20; -; 1; . InterPro IPR000308; 14-3-3; . InterPro IPR023409; 14-3-3_CS; . InterPro IPR023410; 14-3-3_domain; . PANTHER PTHR18860; PTHR18860; 1; . Pfam PF00244; 14-3-3; 1; . PIRSF PIRSF000868; 14-3-3; 1; . PRINTS PR00305; 1433ZETA; . SMART SM00101; 14_3_3; 1; . SUPFAM SSF48445; SSF48445; 1; . PROSITE PS00796; 1433_1; 1; . PROSITE PS00797; 1433_2; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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